کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
18666 42732 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reduction of carbon–carbon double bonds using Acetobacterium woodii: Determination of the optimum inducer structure
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Reduction of carbon–carbon double bonds using Acetobacterium woodii: Determination of the optimum inducer structure
چکیده انگلیسی

Various cinnamate derivatives were tested as inducers for reduction of C–C double bonds in Acetobacterium woodii. The double bond and a phenyl ring were essential for induction, since crotonate and hydrocaffeate were ineffective as inducers whereas cinnamate derivatives were effective. Induction was improved by ring hydroxylation, except in the 2-position, since caffeate and 3- and 4-hydroxy cinnamate were the most effective inducers. The carboxylate group of cinnamate could be replaced by ester (methylcinnamate) or aldehyde (cinnamaldehyde), but not by alcohol (cinnamyl alcohol) or methyl (trans-β-methylstyrene). Effective inducers were hydrogenated efficiently during growth, whereas ineffective inducers were not metabolised. Several inducers with intermediate effectiveness were hydrogenated in low yield with accompanying metabolism of other functional groups. Overall, caffeate (3,4-dihydroxycinnamate) was the best inducer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Enzyme and Microbial Technology - Volume 39, Issue 5, 4 September 2006, Pages 1066–1071
نویسندگان
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