کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1877178 | 1042051 | 2008 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Biological investigation of 131I-labeled new water soluble Ru(II) polypyridyl complex
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
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چکیده انگلیسی
New [Ru(L1)(dcbpy)(NCS)2] complex was synthesized in a one-pot reaction starting from [RuCl2(p-cymene)]2, where the ligands (dcbpy=4,4′-dicarboxy-2,2′-bipyridine, L1=dipyrido[3,2-a:2′,3′-c]phenazine-11-ylcarbonyl)-sodium) are introduced sequentially. The resulting complex was characterized by IR, NMR, and elemental analysis. The complex was labeled with I-131. Biodistribution study of the complex was carried out using 131I-labeled [Ru(L1)(dcbpy)(NCS)2] complex. The biodistribution study performed with albino Wistar male rats has shown that the complex has high uptake in the lung, small intestine, fat, and spleen.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 66, Issue 2, February 2008, Pages 115–121
Journal: Applied Radiation and Isotopes - Volume 66, Issue 2, February 2008, Pages 115–121
نویسندگان
Kasim Ocakoglu, Yeliz Yildirim, Fatma Yurt Lambrecht, Jale Ocal, Siddik Icli,