کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1887426 | 1533547 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Radiosynthesis of hydrogel confined to hollow-fiber membranes for the design of a bioartificial extra-corporeal liver
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
تشعشع
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
We demonstrate the feasibility to synthesize the hydrogels confined to the macroporous structure of membranes by radiation-induced in situ polymerization. The hollow-fiber membranes were soaked in aqueous monomeric solution, rinsed and irradiated while submerged in oil. This procedure confined the hydrogel to the void internal volume of the pores of the membrane. Hydrogels of polyacrylamide and polyHEMA were synthesized this way by irradiation at 10Â kGy. Hydraulic permeability and diffusion of glucose, albumin and IgG were measured in these hydrogel-filled membranes. Polyacrylamide 0.5Â M showed the best compromise between albumin diffusion (1.2Ã10â7Â cm2/s) and HSA/IgG selectivity (2.2).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiation Physics and Chemistry - Volume 76, Issues 8â9, AugustâSeptember 2007, Pages 1419-1424
Journal: Radiation Physics and Chemistry - Volume 76, Issues 8â9, AugustâSeptember 2007, Pages 1419-1424
نویسندگان
R. Hidalgo, N. Vizioli, E.E. Smolko, P. Argibay, M. Grasselli,