کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1907197 1046338 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Counting calories in Drosophila diet restriction
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Counting calories in Drosophila diet restriction
چکیده انگلیسی

The extension of life span by diet restriction in Drosophila has been argued to occur without limiting calories. Here we directly measure the calories assimilated by flies when maintained on full- and restricted-diets. We find that caloric intake is reduced on all diets that extend life span. Flies on low-yeast diet are long-lived and consume about half the calories of flies on high-yeast diets, regardless of the energetic content of the diet itself. Since caloric intake correlates with yeast concentration and thus with the intake of every metabolite in this dietary component, it is premature to conclude for Drosophila that calories do not explain extension of life span.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Gerontology - Volume 42, Issue 3, March 2007, Pages 247–251
نویسندگان
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