Management of squamous cell carcinoma of the head and neck in the elderly: Review and recommendations

In general, the management and reported outcomes for elderly patients with squamous cell carcinoma of the head and neck (SCCHN) have been similar to those of younger patients. But older adults are a distinct subpopulation of patients who differ from younger patients due to their increased risks for: comorbidities, decreased functional status, a potential decline in cognitive function and an increase in vulnerabilities. Older adults have been underrepresented in the clinical trials which define our best treatment strategies. This review explores the evidence used to establish common practice in managing SCCHN and evaluates the relevance of this evidence for the older adult, concluding with recommendations based on the review.