Epigallocatechin gallate (EGCG) inhibits type II phosphatidylinositol 4-kinases: A key component in pathways of phosphoinositide turnover

► EGCG inhibits type II Phosphatidylinositol (PtdIns) 4-kinase α and β isoforms. ► EGCG has differential interaction with both the isoforms revealed by spectroscopy. ► Autodock mapped the binding residues at ATP binding domain of PtdIns 4-kinase.