New type of kdp region with a split sensor-kinase kdpD gene located within two divergent kdp operons from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius

The kdp region from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius consists of two divergent operons: kdpZFABCN, which is tenfold induced at low K+ concentrations and encodes the K+-translocating P-type ATPase KdpZFABC as well as KdpN, a novel covalent homo-dimer of the cytoplasmic N-terminal part from sensor kinase KdpD; and secondly, the constitutively expressed kdpHE operon, encoding the remainder of KdpD and the response regulator KdpE.