The antimicrobial peptide arenicin-1 promotes generation of reactive oxygen species and induction of apoptosis

► Arenicin-1 increased ROS generation in C. albicans cells. ► Arenicin-1 may induce formation of hydroxyl radical. ► Arenicin-1 activates metacaspases in yeast. ► Arenicin-1 can induce apoptosis.