کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1949844 1537785 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases
چکیده انگلیسی

Phosphatidic acid (PA) production by receptor-stimulated phospholipase D is believed to play an important role in the regulation of cell function. The second messenger function of PA remains to be elucidated. PA can bind and affect the activities of different enzymes and here we summarise the current status of activation of Type I phosphatidylinositol 4-phosphate 5-kinase by PA. Type 1 phosphatidylinositol 4-phosphate 5-kinase is also regulated by ARF proteins as is phospholipase D and we discuss the contributions of ARF and PA towards phosphatidylinositol(4,5)bisphosphate synthesis at the plasma membrane.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids - Volume 1791, Issue 9, September 2009, Pages 905–912
نویسندگان
,