کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1953385 | 1538437 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Interferon-γ is produced by another player of innate immune responses: The interferon-producing killer dendritic cell (IKDC)
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Interferon-γ is produced by another player of innate immune responses: The interferon-producing killer dendritic cell (IKDC) Interferon-γ is produced by another player of innate immune responses: The interferon-producing killer dendritic cell (IKDC)](/preview/png/1953385.png)
چکیده انگلیسی
Interferon-γ is a key cytokine in tumor immunosurveillance. The recently described interferon-producing killer dendritic cell (IKDC), can be distinguished from other innate effectors by its ability to kill a large variety of tumor cells and to produce high amounts of interferon-γ after encountering tumors in the absence of exogenous cytokines. The cytotoxic activity of IKDC was unraveled during an efficient immunotherapy combining c-kit tyrosine kinase inhibitors and interleukin-2, and is mediated through tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and interferon type IIR.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimie - Volume 89, Issues 6–7, June–July 2007, Pages 872–877
Journal: Biochimie - Volume 89, Issues 6–7, June–July 2007, Pages 872–877
نویسندگان
Mathieu Bonmort, Evelyn Ullrich, Grégoire Mignot, Bénédikt Jacobs, Nathalie Chaput, Laurence Zitvogel,