کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1967032 | 1538735 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Laboratory, clinical and therapeutic aspects of acquired hemophilia A
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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چکیده انگلیسی
Acquired hemophilia A is a rare bleeding diathesis caused by autoantibodies directed against clotting factor VIII and associated with an increased morbidity and mortality. This disease occurs most commonly in the elderly, and although it may be associated with a variety of underlying pathological conditions, up to 50% of reported cases remain idiopathic.In this review, we report the present knowledge on the most important laboratory, diagnostic and clinical aspects of acquired hemophilia A. Moreover, we focus on the most recent advances in the treatment of this disorder, which is primarily aimed to control bleeding episodes and to eradicate the autoantibody production.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinica Chimica Acta - Volume 395, Issues 1–2, September 2008, Pages 14–18
Journal: Clinica Chimica Acta - Volume 395, Issues 1–2, September 2008, Pages 14–18
نویسندگان
Massimo Franchini, Giovanni Targher, Martina Montagnana, Giuseppe Lippi,