کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1967811 1538757 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cardiac troponin I serum concentrations in newborns: A study and review of the literature
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Cardiac troponin I serum concentrations in newborns: A study and review of the literature
چکیده انگلیسی

BackgroundSerum cardiac troponin I (cTnI) is a specific marker of cardiac injury. The use of cTnI in neonates, especially in relation to perinatal asphyxia has not been extensively examined. We defined the range of normal values of cTnI in newborns, and study factors that may influence these concentrations.MethodsSerum cTnI concentrations were measured on the third day of life in 179 normal newborns: 157 were term (after 37 weeks, mean: 39.7 ± 1.1, range: 37–42) and 22 were premature infants (mean: 32.6 ± 2.9, range: 27–36 weeks).ResultsMean cTnI for the term infants was 0.63 ± 0.58 ng/ml (median: 0.50, range: 0.00–4.30). The concentration of 1.80 ng/ml, can serve as the upper limit of normal values. There was a borderline significant trend for higher cTnI in preterm infants. The number of newborns with cTnI > 1.80 ng/ml was significantly higher after delivery by caesarean section, compared to vaginal delivery (14.6% vs. 2.9%, p < 0.02). No other significant associations were found between cTnI and perinatal or neonatal parameters.ConclusionsNormal reference values for cTnI in healthy term newborns were defined, but need to be addressed with caution due to the wide range of normal values.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinica Chimica Acta - Volume 371, Issues 1–2, September 2006, Pages 61–65
نویسندگان
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