Positive correlation between galactose-1-phosphate uridyltransferase (GALT) and UDP-galactose-4′-epimerase (GALE) activities

ObjectivesThe aim of our study was to determine whether the activities of galactose-1-phosphate uridyltransferase and UDP-galactose-4′-epimerase are correlated, and in what way they may influence one another.Design and methodsEnzyme activities were measured in red blood cells from 214 individuals.ResultsA statistically significant (p < 0.001) positive correlation was observed between GALT and GALE activities.ConclusionsOur results suggest that GALT and GALE activities are correlated and that GALE activity has a greater impact on GALT activity than vice versa.