کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1970296 | 1538917 | 2007 | 4 صفحه PDF | دانلود رایگان |
Objectives:To assess the ability of C-reactive protein (CRP) to predict long-term outcomes in a chest pain population.Design and methods:CRP was measured at presentation in 446 emergency department patients with acute coronary syndromes. All-cause mortality and hospital discharges for acute myocardial infarction (AMI) and congestive heart failure (CHF) were obtained for up to 8 years following the event.Results:Kaplan–Meier analyses indicated that patients with CRP concentrations above the American Heart Association scientific statement cut-off had a higher rate for death and CHF admissions. After adjusting for troponin concentrations, in a Cox proportional hazard model, only CRP concentrations indicative of an acute phase response (i.e., > 7.44 mg/L) were associated with a significant risk for death after 5 years and CHF readmission after 2 years.Conclusions:Patients presenting early with chest pain with elevated CRP concentrations have a greater long-term risk for death and heart failure.
Journal: Clinical Biochemistry - Volume 40, Issues 5–6, March 2007, Pages 326–329