A cross-sectional study of the association between heat shock protein 27 antibody titers, pro-oxidant-antioxidant balance and metabolic syndrome in patients with angiographically-defined coronary artery disease

► Anti-Hsp27 titres were elevated in patients with concurrent CAD and metabolic syndrome compared to those with only CAD. ► Serum prooxidant-antioxidant balance was not elevated in the metabolic syndrome group beyond what is caused by CAD. ► Accumulation of MS features in patients with CAD could be associated with increased risk of vascular complications.