کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1979600 | 1061688 | 2006 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The types and prevalence of alternative splice forms
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The types and prevalence of alternative splice forms The types and prevalence of alternative splice forms](/preview/png/1979600.png)
چکیده انگلیسی
The finding that eukaryotic gene structures are extremely complex prompted the development of new experimental techniques for the accurate measurement of transcription start site usage and of the expression of alternative splice forms. On the computational side, analyses of large databases of splice variants revealed differences in the length, motif composition and selection pressure between constitutive and alternatively spliced exons. Such features are being incorporated into novel computational tools for gene structure prediction. The result of these investigations is a continuously improving catalogue of alternative splice forms. How the expression of these alternative splice forms is regulated remains one of the major open questions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Structural Biology - Volume 16, Issue 3, June 2006, Pages 362–367
Journal: Current Opinion in Structural Biology - Volume 16, Issue 3, June 2006, Pages 362–367
نویسندگان
Mihaela Zavolan, Erik van Nimwegen,