کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1979909 | 1061711 | 2008 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Predicting novel RNA-RNA interactions
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
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چکیده انگلیسی
The purpose of this article is to give a brief, yet concise overview of the current computational methods for predicting novel RNA-RNA interactions, that is interactions whose characteristic features we do not yet know. We start by briefly reviewing experimentally confirmed examples of RNA-RNA interactions before introducing computational methods for predicting RNA-RNA interactions. We will focus primarily on the interactions between different RNA molecules, that is trans RNA-RNA interactions, and will only discuss methods for predicting RNA structure, that is cis-only RNA-RNA interactions, where this helps to gain a better understanding. We conclude by discussing the merits of the different approaches and provide an outlook on probably and desirable future developments in the field.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Structural Biology - Volume 18, Issue 3, June 2008, Pages 387-393
Journal: Current Opinion in Structural Biology - Volume 18, Issue 3, June 2008, Pages 387-393
نویسندگان
Irmtraud M Meyer,