Srs2 enables checkpoint recovery by promoting disassembly of DNA damage foci from chromatin

► Maintenance of checkpoint arrest correlates with chromatin association of Ddc2-Mec1. ► Chromatin accumulation of 9-1-1 is not necessary for maintenance of a checkpoint arrest. ► ssDNA persists in cells lacking Srs2 following DNA double-strand break repair. ► Srs2-dependent eviction of Rad51 is important to remove checkpoint-inducing ssDNA.