14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

► hEXO1 interacts with 14-3-3 proteins. ► Specific binding by 14-3-3 involves amino acid S746 in hEXO1. ► hEXO1 and 14-3-3 interaction may play a role during DNA damage, signaling and repair.