Insecticidal properties of Sclerotinia sclerotiorum agglutinin and its interaction with insect tissues and cells

► Sclerotinia sclerotiorum agglutinin (SSA) is highly entomotoxic for pea aphids. ► SSA targets the insect midgut with its brush border zone, without internalization. ► SSA induces cell death/apoptosis in midgut cells through binding with specific carbohydrate moieties