Glucose regulates protein kinase CK2 in pancreatic β-cells and its interaction with PDX-1

- CK2 and PDX-1 shuttle glucose dependently from the cytosol into the nucleus.
- Glucose stimulates protein kinase activity of CK2.
- Glucose enhances binding of CK2 to PDX-1.
- CK2 is a co-factor of PDX-1 in the regulation of insulin production in β-cells.