کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1986652 | 1540256 | 2014 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Comparison of hypoglycemic and antioxidative effects of polysaccharides from four different Dendrobium species
ترجمه فارسی عنوان
مقایسه اثر هیپوگلیسمی و آنتی اکسیدانی پلی ساکارید از چهار گونه مختلف دندروبیوم
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کلمات کلیدی
دندروبیوم پلی ساکارید، فعالیت هیپوگلیسمی، فعالیت ضد عفونی کننده،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
چکیده انگلیسی
Four polysaccharides from Dendrobium huoshanense (DHP), D. officinale (DOP), D. nobile (DNP) and D. chrysotoxum (DCP), which had obvious differences in intrinsic viscosities and monosaccharide compositions, were extracted to compare their hypoglycemic and antioxidative activities in alloxan-induced diabetic mice by oral administration. The analysis of fasting blood glucose, glycosylated serum protein and serum insulin levels showed that DHP, DOP and DNP, but not DCP, possessed significant hypoglycemic effect with the decreasing order of DHPÂ >Â DNPÂ >Â DOP. Histopathological observation confirmed the capability of DHP, DOP and DNP to intervene the damage in pancreas tissues. The determination of superoxide dismutase, catalase, malonaldehyde and l-glutathione levels in the liver and kidney displayed that DHP, DOP and DNP had protective effects against alloxan-induced oxidative damage and the effect of DHP ranked first. These results suggested that there were significant differences in hypoglycemic and antioxidative activities between four Dendrobium polysaccharides, which may be contributed to their physicochemical properties.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 64, March 2014, Pages 420-427
Journal: International Journal of Biological Macromolecules - Volume 64, March 2014, Pages 420-427
نویسندگان
Li-Hua Pan, Xiu-Fang Li, Mei-Na Wang, Xue-Qiang Zha, Xue-Fei Yang, Zhong-Jian Liu, Yi-Bo Luo, Jian-Ping Luo,