کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1992519 1541078 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The development of CD-ring modified analogs of 1α,25-dihydroxyvitamin D
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
The development of CD-ring modified analogs of 1α,25-dihydroxyvitamin D
چکیده انگلیسی

During a 20-year collaboration the laboratories of UGent and KU Leuven have developed different series of Vitamin D analogs characterized by structural modifications in the central CD-ring system. Modifications have first involved the introduction of substituents at C11 and the epimerization at C14, and subsequently more drastic changes consisting in both ring deletion and enlargement relative to the natural CD-ring system. Lately, the focus has shifted towards the synthesis of analogs featuring a symmetrical CD-ring core. As an illustration two different series are presented.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Steroid Biochemistry and Molecular Biology - Volume 103, Issues 3–5, March 2007, Pages 206–212
نویسندگان
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