کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1992902 | 1541068 | 2008 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Androgen receptor functions in male and female physiology
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Androgen receptor functions in male and female physiology Androgen receptor functions in male and female physiology](/preview/png/1992902.png)
چکیده انگلیسی
The biological actions of androgens are mediated by transcriptional control of target genes through binding to the androgen receptor (AR). The AR belongs to the nuclear receptor superfamily and acts as a ligand-inducible transcriptional factor. Androgens/AR system is thought to be central to male physiology and behaviors to the development of clinical pathology. The physiological importance of AR function currently recognized in female reproduction also has been verified in mouse genetic model. Here we review functions of AR in male and female physiology as revealed by mice lacking AR.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Steroid Biochemistry and Molecular Biology - Volume 109, Issues 3–5, April 2008, Pages 236–241
Journal: The Journal of Steroid Biochemistry and Molecular Biology - Volume 109, Issues 3–5, April 2008, Pages 236–241
نویسندگان
Takahiro Matsumoto, Hiroko Shiina, Hirotaka Kawano, Takashi Sato, Shigeaki Kato,