کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1994463 1064787 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Translation of an experimental oral vaccine formulation into a commercial product
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Translation of an experimental oral vaccine formulation into a commercial product
چکیده انگلیسی

An effective experimental vaccine may fail to become a therapeutic reality for a number of scientific, regulatory or commercial reasons. In this review, we share some of our personal experiences as University-based researchers and provide an account of some of the problems that we have encountered during preliminary scale-up and assessment of an oral influenza vaccine formulation. Many of the problems we have faced have been non-scientific and related to identifying project-funding sources, finding suitable contract manufacturing companies that are GMP compliant, and protecting intellectual property generated from the scientific studies. The review is intended as a practical guide that will allow other researchers to adopt effective strategies to permit the translation of an effective experimental formulation to a viable commercial product.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Methods - Volume 38, Issue 2, February 2006, Pages 65–68
نویسندگان
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