کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1997747 | 1065614 | 2006 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Divergence from a Dedicated Cellular Suicide Mechanism: Exploring the Evolution of Cell Death
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The developmental cell death in the nematode C. elegans is controlled by a simple and dedicated genetic program. This genetic program is evolutionarily conserved in higher organisms, including mammals. However, although mammalian homologs of C. elegans cell death gene products continue to regulate apoptosis, they are no longer dedicated regulators of cell death. On the other hand, multiple cellular noncell death-related mechanisms have been recruited to regulate cell death under different conditions. Such evidence suggests that evolution has led to an extensive integration of mammalian apoptosis machinery with multiple cellular physiological processes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 23, Issue 1, 7 July 2006, Pages 1–12
Journal: - Volume 23, Issue 1, 7 July 2006, Pages 1–12
نویسندگان
Junying Yuan,