|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|2010740||1066988||2013||10 صفحه PDF||سفارش دهید||دانلود رایگان|
Industrial biotechnology has been defined as the use and application of biotechnology for the sustainable processing and production of chemicals, materials and fuels. It makes use of biocatalysts such as microbial communities, whole-cell microorganisms or purified enzymes. In the review these processes are described.Drug design is an iterative process which begins when a chemist identifies a compound that displays an interesting biological profile and ends when both the activity profile and the chemical synthesis of the new chemical entity are optimized. Traditional approaches to drug discovery rely on a stepwise synthesis and screening program for large numbers of compounds to optimize activity profiles. Over the past ten to twenty years, scientists have used computermodels of newchemical entities to help define activity profiles, geometries and relativities. This article introduces inter alia the concepts ofmolecularmodelling and contains references for further reading.
Journal: Pharmacological Reports - Volume 65, Issue 5, September–October 2013, Pages 1102–1111