CXCL12 impairs the acquisition and extinction of auditory fear conditioning in rats via crosstalk with GABAergic system

Our data suggest that the chemokine CXCL12 is able to regulate neurotransmitter mechanisms involved in associative learning functions, and the effect of GABAergic agents on CXCL12/CXCR4 may be new therapeutic potentials for neuroinflammatory diseases.