کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2012849 1541863 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antidepressant-induced sexual dysfunction in men
ترجمه فارسی عنوان
اختلالات جنسی ناشی از نارسایی مزمن در مردان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
چکیده انگلیسی


• Antidepressant therapy is associated with sexual dysfunction
• Sexual dysfunction is more common with drugs that increase serotonergic activity
• Sexual dysfunction is less common with drugs with dopaminergic activity
• Sexual dysfunction is less common with drugs with an adrenergic mechanism of action

Most of the available antidepressant medications, including tricyclic antidepressants, monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, and dual noradrenergic/serotonergic reuptake inhibitors have been reported to be associated with sexual dysfunction in both sexes. This manuscript reviews evidence concerning the relative incidence of treatment emergent sexual dysfunction in men being treated with antidepressant drugs. Both double-blind controlled trials and large clinical series report a high incidence of sexual dysfunction, especially ejaculatory delay, with serotonergic drugs. The incidence of sexual dysfunction in men appears to be much lower with drugs whose primary mechanism of action involves adrenergic or dopaminergic systems.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacology Biochemistry and Behavior - Volume 121, June 2014, Pages 132–137
نویسندگان
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