Proteomic changes in different growth periods of ginseng roots

► Proteomics and biochemical variables unravel the growth strategies of ginseng. ► Enzyme activities and metabolite contents were changed in different growth phases. ► Ginseng in the fast growth period prepares for energy to promote root elongation. ► Ginseng gains the energy for improving metabolism and defence in slow-growth period. ► The supposed model explained the interactions of energy proteins in ginseng growth.