Biochemical properties of three plant nucleases with anticancer potential

▶ Broad substrate specificity of all three nucleases. ▶ Resistance of poly(G) to nucleolytic degradation. ▶ Poly(G) is a strong inhibitor of all three nucleases. ▶ Computation of 3-D models of the nucleases, tools for further investigation. ▶ Confirmation of an anti-tumor activity of ABN1.