کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2019376 1542180 2007 25 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Probing phospholipid dynamics by electrospray ionisation mass spectrometry
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
پیش نمایش صفحه اول مقاله
Probing phospholipid dynamics by electrospray ionisation mass spectrometry
چکیده انگلیسی

Recent advances in electrospray ionisation mass spectrometry (ESI-MS) have greatly facilitated the analysis of phospholipid molecular species in a growing diversity of biological and clinical settings. The combination of ESI-MS and metabolic labelling employing substrates labelled with stable isotopes is especially exciting, permitting studies of phospholipid synthesis and turnover in vivo. This review will first describe the methodology involved and will then detail dynamic lipidomic studies that have applied the stable isotope incorporation approach. Finally, it will summarise the increasing number of studies that have used ESI-MS to characterise structural and signalling phospholipid molecular species in development and disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Lipid Research - Volume 46, Issues 3–4, May–July 2007, Pages 200–224
نویسندگان
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