Participation of extracellular Ca2+ or ghrelin in peptide-mediated contraction of strips from rat urinary bladder

Our experimental data indicate that the increase of calcium in the extracellular fluid possesses a synergistic effect on the neuropeptide-mediated contraction. The effects of ghrelin on Ang II- and AVP-mediated contractions allow us to express the assumption that the urinary bladder cells probably have ghrelin receptors which do not activate phospholipase C signal pathway.