کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2023125 1542435 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neuropeptide Y (NPY) Y2 receptors of rabbit kidney cortex are largely dimeric
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Neuropeptide Y (NPY) Y2 receptors of rabbit kidney cortex are largely dimeric
چکیده انگلیسی
The neuropeptide Y (NPY) Y2 receptors and the pancreatic polypeptide Y4 receptors from rabbit kidney cortex are isolated largely as ∼ 180 kDa complexes constituted of one receptor dimer and one G-protein heterotrimer, similar to NPY receptors expressed in the Chinese hamster ovary (CHO) cells. As expected, kidney and CHO cell Y2 dimers are converted into monomers by increasing concentrations of a selective agonist. Prevalence of dimeric Y2 receptors in the kidney could be related to low plasma levels of Y2 agonists, and possibly also to a relatively low concentration of Gi α subunits.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regulatory Peptides - Volume 150, Issues 1–3, 9 October 2008, Pages 88-94
نویسندگان
, , , , , ,