کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2023369 1542446 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Total ghrelin plasma level in patients with the restrictive type of anorexia nervosa
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Total ghrelin plasma level in patients with the restrictive type of anorexia nervosa
چکیده انگلیسی

Ghrelin is produced mainly in the stomach and is an essential link of the brain–gut axis. Ghrelin stimulates hunger centers in hypothalamus controlling food intake and body mass gain. The aim of the study is to analyze the total ghrelin plasma level in patients suffering from restrictive type of anorexia nervosa (AN-R). According to DSM-IV classification a group of 30 AN-R patients was investigated before and after 3 and 6 months of therapy. Therapy included normocaloric diet and cognitive–behavioral psychotherapy (CBT). The control group consisted of 20 girls without any eating disorders. Before the therapy the total ghrelin plasma level in AN-R patients was significantly higher than in the control group. After 3 and 6 months of treatment the total ghrelin plasma level in AN-R patients was significantly lower than in the control group. In AN-R patients, the total ghrelin plasma level is connected with the pathological feeding behavior.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regulatory Peptides - Volume 140, Issues 1–2, 5 April 2007, Pages 43–46
نویسندگان
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