کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2034862 1072107 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A hypothesis on the role of primitive macrophages in initial embryonic lymphatic development
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
پیش نمایش صفحه اول مقاله
A hypothesis on the role of primitive macrophages in initial embryonic lymphatic development
چکیده انگلیسی

Recent evidences have shown that macrophages are tightly related to pathological lymphangiogenesis. However, the effects which primitive macrophages take in embryonic lymphatic development remains unclear. Here, we postulate that the primitive macrophages may play an important role in initial embryonic lymphatic development. The possible mechanism: primitive macrophages induce BECs to transdifferentiate into LECs and initiate the budding, moreover, the lymph sacs are not only formed by LECs but also some scattered cells with macrophage characteristics preferentially located in the loose mesenchyme.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioscience Hypotheses - Volume 2, Issue 5, 2009, Pages 302–305
نویسندگان
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