کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2067352 | 1077894 | 2008 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of tyrosine kinase and phosphatase inhibitors on microtubules in Arabidopsis root cells
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کلمات کلیدی
MTSHerbimycin APTKs - PTK هاPTPs - PTP هاArabidopsis thaliana - آرابیدوپسیس تالیاناsodium orthovanadate - سدیم ارتوواناداتTyrosine phosphorylation - فسفوریلاسیون تروفوزینInhibitors - مهارکنندهMicrotubules - میکروتوبول، ریزلوله هاprotein tyrosine phosphatases - پروتئین تیروزین فسفاتازProtein tyrosine kinases - پروتئین تیروزین کیناز
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوفیزیک
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
To investigate the role of tyrosine phosphorylation/dephosphorylation processes in plant cells the morphology of Arabidopsis thaliana primary roots and the organization of cortical microtubules (MTs) were studied after inhibition of protein tyrosine kinases (PTKs) and tyrosine phosphatases (PTPs). It was found that all tested types of PTKs inhibitors (herbimycin A, genistein and tyrphostin AG 18) altered root hair growth and development, probably as a result of their significant influences on MTs organization in root hairs. The treatment also led to MTs reorientation and disruption in epidermis and cortex cells of both elongation and differentiation zones of primary roots. Enhanced tyrosine phosphorylation after treatment with a PTPs inhibitor (sodium orthovanadate) resulted in intense induction of root hair development and growth and caused a significant shortening of the elongation zone. It also led to changes of MTs orientation from transverse to longitudinal in epidermis and cortex cells of the elongation and differentiation zones of the root. From the data obtained we can suppose that tyrosine phosphorylation can be involved in the dynamics and organization of MTs in different types of plant cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cell Biology International - Volume 32, Issue 6, June 2008, Pages 630-637
Journal: Cell Biology International - Volume 32, Issue 6, June 2008, Pages 630-637
نویسندگان
Alla Yemets, Yarina Sheremet, Kris Vissenberg, Jürgen Van Orden, Jean-Pierre Verbelen, Yaroslav B. Blume,