کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2071002 | 1078715 | 2013 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Therapeutic platforms based on gold nanoparticles and their covalent conjugates with drug molecules
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوتکنولوژی یا زیستفناوری
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
This review will first look at the various covalent strategies that have been developed to attach drugs to gold nanoparticles as well as the strengths and limitations of such strategies. After examining general strategies for the synthesis of gold nanoparticles and their subsequent covalent functionalization, this review will focus on nanoparticle conjugates for gene therapy, antibacterial, and anticancer applications including the use of gold nanoparticles with intrinsically therapeutic properties. The effects of targeting and cellular uptake of gold nanoparticles will also be discussed.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advanced Drug Delivery Reviews - Volume 65, Issue 5, May 2013, Pages 663–676
Journal: Advanced Drug Delivery Reviews - Volume 65, Issue 5, May 2013, Pages 663–676
نویسندگان
Leonid Vigderman, Eugene R. Zubarev,