کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2071088 1078721 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Polychromatic in vivo imaging of multiple targets using visible and near infrared light
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Polychromatic in vivo imaging of multiple targets using visible and near infrared light
چکیده انگلیسی

Conventional diagnostic imaging methods such as X-ray CT, MRI, and nuclear medicine are inherently monochromatic meaning that they can depict only one molecular target at a time. Optical imaging has the unique ability to be polychromatic and therefore multi-color imaging employing targeted agents conjugated to fluorophores of varying wavelength enables multiple simultaneous readouts thus providing greater multiplexed information. Numerous successful multicolor imaging techniques have recently been reported using optical imaging in in vivo animal disease models, thus adding to a growing body of research supporting the clinical viability and applicability of these technologies. Herein, we review multicolor optical imaging from the basic chemistry and physics perspective and then extend this to biological and medical applications.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advanced Drug Delivery Reviews - Volume 65, Issue 8, July 2013, Pages 1112–1119
نویسندگان
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