کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2071097 1078722 2012 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Gold nanorods: Their potential for photothermal therapeutics and drug delivery, tempered by the complexity of their biological interactions
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Gold nanorods: Their potential for photothermal therapeutics and drug delivery, tempered by the complexity of their biological interactions
چکیده انگلیسی

Gold nanorods have promising applications in the fields of drug delivery and photothermal therapy. These promises arise from the nanorods' unique optical and photothermal properties, the availability of synthetic protocols that can tune the size and shape of the particles, the ability to modify the surface and conjugate drugs/molecules to the nanorods, and the relative biocompatibility of gold nanorods. In this review, current progress in using gold nanorods as phototherapeutic agents and as drug delivery vehicles is summarized. Issues of dosage, toxicity and biological interactions at three levels (biological media alone; cells; whole organisms) are discussed, concluding with recommendations for future work in this area.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advanced Drug Delivery Reviews - Volume 64, Issue 2, February 2012, Pages 190–199
نویسندگان
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