کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2071162 | 1078728 | 2012 | 21 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Calcium phosphate cements as drug delivery materials Calcium phosphate cements as drug delivery materials](/preview/png/2071162.png)
Calcium phosphate cements are used as synthetic bone grafts, with several advantages, such as their osteoconductivity and injectability. Moreover, their low-temperature setting reaction and intrinsic porosity allow for the incorporation of drugs and active principles in the material. It is the aim of the present work to: a) provide an overview of the different approaches taken in the application of calcium phosphate cements for drug delivery in the skeletal system, and b) identify the most significant achievements. The drugs or active principles associated to calcium phosphate cements are classified in three groups, i) low molecular weight drugs; ii) high molecular weight biomolecules; and iii) ions.
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Journal: Advanced Drug Delivery Reviews - Volume 64, Issue 12, September 2012, Pages 1090–1110