کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2071371 | 1544599 | 2011 | 8 صفحه PDF | دانلود رایگان |

The development of substitutes for the human trachea or its bronchial tree represents a niche application in the rapidly advancing scientific field of Regenerative Medicine. Despite a comparatively small research foundation in the field of tracheo-bronchial bioengineering, four different approaches have already been translated into clinical settings and applied in patients. This can be attributed to the lack of established treatment options for a small group of patients with extensive major airway disease. In this review, the clinical background and tissue-specific basics of tracheo-bronchial bioengineering will be evaluated. Focusing on the clinical applications of bioengineered tracheal tissues, a “top–down” or “bedside-to-bench” analysis is performed in order to guide future basic and clinical research activities for airway bioengineering.
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Journal: Advanced Drug Delivery Reviews - Volume 63, Issues 4–5, 30 April 2011, Pages 367–374