کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2076977 | 1545001 | 2007 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Information about a form (on the dynamic laws of morphogenesis)
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موضوعات مرتبط
مهندسی و علوم پایه
ریاضیات
مدلسازی و شبیه سازی
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چکیده انگلیسی
How a developing embryo becomes “informed” about its form?” This problem remains obscure and controversial. We argue that the “information about a form” is distributed throughout three main components: the dynamic laws, the parameters and the initial/boundary conditions. In the absence of a dynamic law two other components are “blind”, that is, do not contain any unambiguous information. We present a version of a dynamic law of morphogenesis, based upon the presumption of a feedback between passive and active mechanical stresses. We explore several models of shape formation based upon this law and show that, as depending upon the parameters values, they generate a large set of realistic shapes. Genetic and epigenetic basis of the models parameters is discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosystems - Volume 87, Issues 2â3, February 2007, Pages 204-214
Journal: Biosystems - Volume 87, Issues 2â3, February 2007, Pages 204-214
نویسندگان
Lev V. Beloussov, Vassily I. Grabovsky,