کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2079245 1079852 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
SMALL WORLD NETWORK STRATEGIES FOR STUDYING PROTEIN STRUCTURES AND BINDING
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
SMALL WORLD NETWORK STRATEGIES FOR STUDYING PROTEIN STRUCTURES AND BINDING
چکیده انگلیسی

Small world network concepts provide many new opportunities to investigate the complex three dimensional structures of protein molecules. This mini-review explores the published literature on using small-world network approaches to study protein structure, with emphasis on the different combinations of descriptors that have been tested, on studies involving ligand binding in protein-ligand complexes, and on protein-protein complexes. The benefits and success of small world network approaches, which change the focus from specific interactions to the local environment, even to non-local phenomenon, are described. The purpose is to show the different ways that small world network concepts have been used for building new computational models for studying protein structure and function, and for extending and improving existing modelling approaches.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computational and Structural Biotechnology Journal - Volume 5, Issue 6, February 2013, Pages 1–7
نویسندگان
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