کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2089842 | 1545933 | 2015 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Novel multiplex format of an extended multilocus variable-number-tandem-repeat analysis of Clostridium difficile correlates with tandem repeat sequence typing
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوتکنولوژی یا زیستفناوری
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Novel multiplex format of an extended multilocus variable-number-tandem-repeat analysis of Clostridium difficile correlates with tandem repeat sequence typing Novel multiplex format of an extended multilocus variable-number-tandem-repeat analysis of Clostridium difficile correlates with tandem repeat sequence typing](/preview/png/2089842.png)
چکیده انگلیسی
• We successfully developed a multiplex MLVA format for subtyping of C. difficile.
• An excellent concordance between MLVA and TRST typing was found.
• We found loci potentially reducible in outbreak investigations of known TRST types.
• We identified variable loci providing discriminatory power to the MLVA scheme.
Subtyping of Clostridium difficile is crucial for outbreak investigations. An extended multilocus variable-number tandem-repeat analysis (eMLVA) of 14 variable number tandem repeat (VNTR) loci was validated in multiplex format compatible with a routine typing laboratory and showed excellent concordance with tandem repeat sequence typing (TRST) and high discriminatory power.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Microbiological Methods - Volume 110, March 2015, Pages 98–101
Journal: Journal of Microbiological Methods - Volume 110, March 2015, Pages 98–101
نویسندگان
Mie Birgitte Frid Jensen, Jørgen Engberg, Jonas T. Larsson, Katharina E.P. Olsen, Mia Torpdahl,