کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2096016 1082149 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The non-human primate oocyte and embryo as a model for women, or is it vice versa?
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
The non-human primate oocyte and embryo as a model for women, or is it vice versa?
چکیده انگلیسی

The role of the non-human primate (NHP) oocyte and embryo in translational research is considered here including both in vitro activities directly involving oocytes or embryos as well as animal studies that impact reproductive function. Reasons to consider NHPs as animal research models along with their limitations are summarized. A case is made that in limited instances, such as in the development and application of the assisted reproductive technologies or in the study of embryonic stem cells, the human oocyte and embryo have acted as models for the monkey. The development of strategies for the preservation of fertility is used as an example of ongoing research in the non-human primate that cannot be conducted in women for ethical reasons. In animal studies, monitoring reproductive potential, responses to embryonic stem cell transplantation, along with translational research in the field of contraceptive development for women are considered as subjects that benefit from the availability of a NHP model.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Theriogenology - Volume 69, Issue 1, January 2008, Pages 31–36
نویسندگان
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