کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2144925 1088639 2011 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Formation of lamellar cross bridges in the annulus fibrosus of the intervertebral disc is a consequence of vascular regression
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Formation of lamellar cross bridges in the annulus fibrosus of the intervertebral disc is a consequence of vascular regression
چکیده انگلیسی
The AF lamellar architecture is established early in development. It later becomes disrupted as a consequence of vascularization. Blood vessels then recede, perhaps due to increasing mechanical stresses in the surrounding matrix. In this study we present evidence that the pathways left by receding blood vessels remain as lamellar cross bridges. It is unclear whether the presence of cross bridges in the aging and degenerating intervertebral disc would be advantageous or detrimental, and this question should be addressed by future studies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Matrix Biology - Volume 30, Issue 4, May 2011, Pages 267-274
نویسندگان
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