کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2156232 1090450 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Epithelioid angiomatous nodule of head and neck
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Epithelioid angiomatous nodule of head and neck
چکیده انگلیسی

Epithelioid vascular proliferations comprise a wide morphologic spectrum, ranging from reactive hyperplasia via benign tumor to malignant conditions. Epithelioid angiomatous nodule (EAN) is a recently recognized benign vascular proliferation with distinct clinical and pathological features.We review the literature and present six additional EANs in the head and neck examined by immunohistochemistry.This series comprised an equal number of males (n=3) and females (n=3) aged 13–45 years (mean 25.8 years). The sites of origin included the tongue (n=2), skin of the lip (n=2), periorbital and temporal skin (n=1), and nose (n=1). A painless solitary nodule (n=4) was the most common presentation. The lesions were distributed in the epidermis and subcutis, with a characteristic unilobular solid proliferation of polygonal epithelioid endothelial cells with intracytoplasmic primitive lumina.The distinction of EAN from other lesions of the heterogeneous group with epithelioid vascular proliferation can usually be made on the basis of the clinical and morphological features. This series indicates that the distribution of EAN in the head and neck region is not uncommon, which is in contrast to what was initially thought. EAN may be a variant of epithelioid hemangioma.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pathology - Research and Practice - Volume 205, Issue 11, 15 November 2009, Pages 753–757
نویسندگان
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