Extracellular domain of human 4-1BBL enhanced the function of cytotoxic T-lymphocyte induced by dendritic cell

► Ex4-1BBL is a recombinant extracellular domain of human 4-1BBL. ► Ex4-1BBL acts as costimulatory signal in the DC-mediated CTL activation. ► Ex4-1BBL enhanced the DC-CTL-mediated specific cytotoxicity. ► Ex4-1BBL is a promising adjuvant for cancer immunotherapy.