Keywords: DC; dendritic cell; TAA; tumour associated antigen; NC; nucleocapsid; MA; matrix; CA; capsid; RRE; rev response element; cppt; central DNA flap; WPRE; woodchuck post-transcriptional response element; TCR; T cell receptor; pMHC; peptide-MHC complex; Th;
مقالات ISI (ترجمه نشده)
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Protective C allele of the single-nucleotide polymorphism rs1335532 is associated with strong binding of Ascl2 transcription factor and elevated CD58 expression in B-cells
Keywords: Antigen-presenting cells; Costimulation; CD2; Monocytes; Treg cells; Wnt signaling pathway;
CD137: A checkpoint regulator involved in atherosclerosis
Keywords: Inflammation; Tumor necrosis factor receptor superfamily; 4-1BB; Vascular inflammation; Cardiovascular disease; Costimulation; Leukocytes;
Involvement of Ly6C, 4-1BB, and KLRG1 in the activation of lamina propria lymphocytes in the small intestine of sanroque mice
Keywords: Costimulation; Inflammation; Intestine; Proinflammatory cytokine; Roquin; ICOS; inducible costimulator; IELs; intraepithelial lymphocytes; KLRG1; killer cell lectin-like receptor subfamily G member 1; LPLs; lamina propria lymphocytes; LCA; leukocyte commo
Research paperFunctional analysis of acquired CD28 mutations identified in cutaneous T cell lymphoma
Keywords: CD28; Costimulation; Cutaneous T cell lymphoma;
EFIS Lecture: Understanding the CTLA-4 checkpoint in the maintenance of immune homeostasis
Keywords: CTLA-4; Autoimmunity; T-cells; Costimulation; CD28; Tolerance;
Development of CAR T cells designed to improve antitumor efficacy and safety
Keywords: 28z; CD28 + CD3ζ; 4-1BBL; 4-1BB ligand; B-ALL; B cell acute lymphatic leukemia; BBz; 4-1BB + CD3ζ; CAR; chimeric antigen receptor; CD40L; CD40 ligand; CRS; cytokine release syndrome; CTLA-4; cytotoxic T-lymphocyte associated protein 4; DCs; dendriti
Agonistic 4-1BB antibody fails to reduce disease burden during acute respiratory syncytial virus (RSV) infection
Keywords: Respiratory syncytial virus (RSV); Agonistic 4-1BB antibody; CD8 T cells; Costimulation;
Pour comprendre : l'activation lymphocytaire T
Keywords: Lymphocytes T; Cellules dendritiques; Complexe majeur; d'histocompatibilité; Molécules de; costimulation; Points de contrôle; immunologiques; T cells; Dendritic cells; Major histocompatibility; complex; Costimulatory molecules; Immune checkpoints;
Analysis of a Genetic Polymorphism in the Costimulatory Molecule TNFSF4 with Hematopoietic Stem Cell Transplant Outcomes
Keywords: Gene polymorphism; Costimulation; Hematopoietic stem cell transplantation; Outcomes; Infection; GVHD
An adenoviral cancer vaccine co-encoding a tumor associated antigen together with secreted 4-1BBL leads to delayed tumor progression
Keywords: Adenoviral vectors; 4-1BBL; Cancer; Vaccine; Costimulation; T cells;
Assessment of costimulation and coinhibition in a triple parameter T cell reporter line: Simultaneous measurement of NF-κB, NFAT and AP-1
Keywords: ANOVA; analysis of variance; APC; allophycocyanin; CsA; Cyclosporin A; CAR; chimeric antigen receptor; CFP; cyan fluorescent protein; gMFI; geometric mean of fluorescence intensity; MP; minimal promoter; NIP45; NFAT-interacting protein; RE; response eleme
NKG2D receptor activation of NF-κB enhances inflammatory cytokine production in murine effector CD8+ T cells
Keywords: NKG2D, Natural Killer Group 2 D; TCR, T cell receptor; PI3K, phosphatidylinositol-3 kinase; IFN, interferon; IL, interleukin; TNF, tumor necrosis factor; LT, lymphotoxin; FasL, fas ligandDAP10; Immunotherapy; Costimulation; NF-κB; CD8T cell; Cytokine
Improving the Th1 cellular efficacy of the lead Yersinia pestis rF1-V subunit vaccine using SA-4-1BBL as a novel adjuvant
Keywords: 4-1BB; CD137; 4-1BBL; SA-4-1BBL; Alum; Plague; Subunit vaccine; rF1-V; Th1 response; Costimulation; Adjuvant;
OX40 ligand regulates splenic CD8− dendritic cell-induced Th2 responses in vivo
Keywords: OX40 ligand; Costimulation; Th2 response; Dendritic cell
The activation of the adaptive immune system: Cross-talk between antigen-presenting cells, T cells and B cells
Keywords: Dendritic cells; T cells; B cells; Costimulation;
Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors
Keywords: Immune Regulation; Costimulation; T-Cell Exhaustion; Inflammation; CMV; cytomegalovirus; HCV; hepatitis C virus; IHL; intrahepatic lymphocyte; PBMC; peripheral blood mononuclear cell;
Immune adjuvants as critical guides directing immunity triggered by therapeutic cancer vaccines
Keywords: costimulation; homing signal; immune adjuvants; polarizing signal; therapeutic cancer vaccines
Increasing the ex vivo antigen-specific IFN-γ production in subpopulations of T cells and NKp46+ cells by anti-CD28, anti-CD49d and recombinant IL-12 costimulation in cattle vaccinated with recombinant proteins from Mycobacterium avium subspecies paratub
Keywords: Costimulation; IFN-γ; T cells; Flow cytometry; Cattle;
Complement Regulation of T-Cell Alloimmunity
Keywords: Allograft rejection; complement; costimulation; T cells; transplantation;
Enhanced costimulation by CD70Â + B cells aggravates experimental autoimmune encephalomyelitis in autoimmune mice
Keywords: Experimental autoimmune encephalomyelitis; CD70; B lymphocyte; T lymphocyte; Costimulation; Regulatory T cell;
BTNL8, a butyrophilin-like molecule that costimulates the primary immune response
Keywords: BTN; butyrophilin; Costimulation; Cell activation; T cells; Cytokines;
Depletion of regulatory T cells by targeting folate receptor 4 enhances the potency of a GM-CSF-secreting tumor cell immunotherapy
Keywords: Cancer immunotherapy; T cells; Tregs; Costimulation;
Asthma and lower airway diseaseProgrammed cell death ligand 2 regulates TH9 differentiation and induction of chronic airway hyperreactivity
Keywords: Asthma; chronic airway hyperreactivity; Aspergillus fumigatus; TH9; costimulation; programmed cell death ligand 2; TGF-β; AHR; Airway hyperreactivity; Cdyn; Dynamic compliance; DC; Dendritic cell; IRF4; Interferon regulatory factor 4; LN; Lymph node; OVA
Equivalent functions for B7.1 and B7.2 costimulation in mediating host resistance to Mycobacterium tuberculosis
Keywords: Mycobacterium tuberculosis; Costimulation; B7.1; B7.2; Th1; Granuloma; Mouse
Human decidual macrophages suppress IFN-γ production by T cells through costimulatory B7-H1:PD-1 signaling in early pregnancy
Keywords: Costimulation; B7-H1; Decidual macrophage; Human pregnancy
Differential peptide binding to CD40 evokes counteractive responses
Keywords: Leishmania; Macrophages; CD40; CD40-ligand; Costimulation
Gene transfer of human CD40Ig does not prevent rejection in a non-human primate kidney allotransplantation model
Keywords: Transplantation; Tolerance; Primate; Costimulation; CD40/CD40L
Tumor PD-L1 co-stimulates primary human CD8+ cytotoxic T cells modified to express a PD1:CD28 chimeric receptor
Keywords: Programmed death 1 (PD-1) receptor; Costimulation; Adoptive T cell therapy;
Interruption of CD28-mediated costimulation during allergen challenge protects mice from allergic airway disease
Keywords: Allergic asthma; costimulation; conditional CD28 knockout mice; ovalbumin; CD28-specific mAb; AHR; Airway hyperresponsiveness; BAL; Bronchoalveolar lavage; CTLA-4; Cytotoxic T lymphocyte-associated antigen 4; CTLA4Ig; Immunoglobulin fused to the extrace
Extracellular domain of human 4-1BBL enhanced the function of cytotoxic T-lymphocyte induced by dendritic cell
Keywords: 4-1BBL; Costimulation; Cytotoxic T lymphocyte; Dendritic cell; Hepatocellular carcinoma;
Distinct responses of splenic dendritic cell subsets to infection with Listeria monocytogenes: Maturation phenotype, level of infection, and T cell priming capacity ex vivo
Keywords: Dendritic cells; Listeria; T cell activation; Costimulation; Innate immunity;
Roles of CD28, CTLA4, and Inducible Costimulator in Acute Graft-versus-Host Disease in Mice
Keywords: T cell; Costimulation; BMT; GVHD
Challenges and opportunities in targeting the costimulation pathway in solid organ transplantation
Keywords: Kidney transplant; Costimulation; Belatacept
Costimulatory signals potently modulate the T cell inhibitory capacity of the therapeutic CD11a antibody Efalizumab
Keywords: T cell activation;; Costimulation;; Immunomodulation;; CD11a;; Biologics
Choice of resident costimulatory molecule can influence cell fate in human naïve CD4+ T cell differentiation
Keywords: Costimulation; Naïve T cell differentiation; Regulatory T cells; ICAM-1; CD28; Foxp3
Function of CD27 in helper T cell differentiation
Keywords: AAI, allergic airway inflammation; APC, antigen presenting cell; TH, helper T cell; TNFR, tumour necrosis factor receptorCD27; CD70; T cell differentiation; Costimulation; Allergic airway inflammation
Insights into the molecular regulation of FasL (CD178) biology
Keywords: Fas ligand; CD178; CD95L; TNF superfamily; Death factor; T lymphocytes; Secretory lysosomes; Degranulation; Signal transduction; Costimulation; Protein–protein-interactions; SH3 domains; Reverse signaling
Incorporation of 4-1BB ligand into an adenovirus vaccine vector increases the number of functional antigen-specific CD8 T cells and enhances the duration of protection against influenza-induced respiratory disease
Keywords: Costimulation; CD8 T cell; Adenovirus vectors; Respiratory infection; Influenza; 4-1BBL;
CTLA-4 (CD152) inhibits T cell function by activating the ubiquitin ligase Itch
Keywords: CFSE; 5,6-carboxyfluorescein diacetate succinimidyl ester; CTLA-4; cytotoxic T lymphocyte antigen-4; PKC-Î; protein kinase C Î; PLC-γ1; phospholipase C-γ1; SHP-2; SH2-domain containing protein tyrosine phosphatase 2; Costimulation; Signal transduction
Receptors and ligands implicated in human T cell costimulatory processes
Keywords: ADA; adenosine deaminase; ALCAM; activated leukocyte cell adhesion molecule; BTLA; B- and T lymphocyte attenuator; BTNL2; butyrophilin-like 2; DAF; decay accelerating factor; DC-SIGN; dendritic cell-specific ICAM-3-grabbing nonintegrin; DR3; death recepto
SA-4-1BBL as the immunomodulatory component of a HPV-16 E7 protein based vaccine shows robust therapeutic efficacy in a mouse cervical cancer model
Keywords: Costimulation; Vaccine; SA-4-1BBL; Adjuvant; Human papillomavirus; Cervical cancer
The DTH effector response and IL-2 are unaffected by cyclosporine A in autoimmune B6D2F1 mice
Keywords: IL-2; Delayed-type hypersensitivity; Cyclosporine A; Cell signaling; Costimulation; T cells; Cytokines; mTOR; Temsirolimus; CTLA-4
T cell stimulator cells, an efficient and versatile cellular system to assess the role of costimulatory ligands in the activation of human T cells
Keywords: T cell activation; Costimulation; TL1A; CD150;
Adaptive immunity and atherosclerosis
Keywords: Atherosclerosis; T cells; Th1; Th2; Regulatory T cells; Costimulation; Coinhibition; Pro-inflammatory cytokines; Anti-inflammatory cytokines; Statins
Hepatitis B Immunology for Clinicians
Keywords: Hepatitis B; Innate immunity; Adaptive immunity; Regulatory T cells; Costimulation; Pathogenesis; Programmed death 1;
Overview of the immune response
Keywords: Adaptive immunity; atopy; B cell; complement; costimulation; inflammation; innate immunity; superantigen; T cell; toleranceAIRE, Autoimmune regulator gene; AMC, Acidic mammalian chitinase; APC, Antigen-presenting cell; CD, Cluster of differentiation; CLP,
Possible involvement of soluble B7-H4 in T cell-mediated inflammatory immune responses
Keywords: Costimulation; B7 family; Contact hypersensitivity; Mouse; T cells
Functional roles for T cell CD40 in infection and autoimmune disease: The role of CD40 in lymphocyte homeostasis
Keywords: CD40; CD8+ T cells; CD4+ T cells; Costimulation; Signaling
Regulation of costimulation in the era of butyrophilins
Keywords: B7; Butyrophilin; Costimulation; BTNL2